U.S. Food and Drug Administration (FDA)

The U.S. Food and Drug Administration (FDA) includes VA/crotonates copolymer on its list of indirect food additives. It may be used as a component of coatings for use as food contact surface of films intended for food packaging.

Expert Panel for Cosmetic Ingredient Safety

The safety of VA/crotonates copolymer has been assessed by the Expert Panel for Cosmetic Ingredient Safety. The Expert Panel evaluated the scientific data and concluded that VA/crotonates copolymer was safe as a cosmetic ingredient. In 2003, as part of the scheduled re-evaluation of ingredients, the Expert Panel considered available new data on VA/crotonates copolymer and reaffirmed the above conclusion.

An aqueous solution containing 3.7% VA/crotonates copolymer and a hair spray containing 13.75% of the ingredient were relatively harmless when administered in single oral doses of up to 50 ml/kg and 5 g/kg, respectively.

These same test materials elicited no skin irritation and minimal, transient eye irritation. Hair spray formulations containing 0.86% of the copolymer caused no skin irritation or sensitization when tested in a repeated insult patch test on humans. On the basis of the available information, VA/crotonates copolymer was considered safe as a cosmetic ingredient.

VA/Crotonates copolymer may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union.